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IODINE LOADING TEST
Abraham
The Iodine/Iodide Loading Test: Important Information
Abraham GE
The official information on the Iodine Loading Test. Describes the tests, procedures, laboratories performing the test, and references.
FLECHAS
Orthoiodosupplementation in a Primary Care Practice
Flechas JD.
The Original Internist, 12(2):89-96, 2005.
"Ideally, all patients should have an iodine loading test prior to orthoiodosupplementation. This test is one in which 50 mg of iodine is given after discard of the first morning void. All urine is collected for the next 24 hours including the first morning urine void the next day. The urine sample is then sent to my laboratory, FFP Laboratory for testing (21). The lab is a CLIA approved high complexity testing laboratory in the state of North Carolina. The testing that is done is using the method as described in previous articles . To date we have done over 3,000 loading tests. Iodine therapy is then instituted using 50 mg/day. The body becomes iodine sufficient in about three months. Please be aware of the difference between micrograms (mcg) and milligrams (mg). One milligram is equal to 1,000 micrograms. The majority of the loading tests that are performed at FFP Lab are on women ages 31 – 70 years old. In 667 patients analyzed, the mean level of excretion was about 18 mg for all age groups no patient achieved whole body sufficiency prior to orthoiodosupplementation. The mean excretion drops, as the population gets older (See Fig. 1-6). This suggests that of a total 50 mg of iodine given, the patients on the average retained a mean of 32 mg into their body on the first go around."
The Iodine/Iodide Loading Test
Flechas, JD.
Vitamin Research Products
"Out of 4,065 tests, less than 1 percent of patients excreted 90 percent or more of the load. About 83 percent of the patients were women and 17 percent were men. The mean iodide output in the 24 hour urine collection was 19.8 mg. In seven to eight percent of the patients evaluated, the amount of iodide excreted was less than 10 percent of the iodine/iodide load (8 percent of female patients and 7 percent male patients) (See Fig. 1 and 2). In men 1 in 682 attained 90 percent sufficiency while in women 1 in 337 did the same. As the patient’s age increases, percent excretion decreased with a mean of 17.7 mg."
VRP STAFF
Testing for Iodine Deficiency. Whole Body Levels Crucial for Thyroid and Breast Health
VRP Staff
Vitamin Research Products
"Testing involves collecting urine immediately upon arising in the morning to use in what’s called a spot test. Then, 50 mg. of potassium iodide and iodine is ingested. Urine is collected throughout the day until the first urine of the next morning. The samples, including the baseline spot test, are shipped to the lab. If the body has sufficient iodine, at least 90 percent will be excreted in the urine. In iodine deficiency, however, the body will hold on to some of the iodine to compensate for the deficiency. The more iodine that remains in the body, the more a person is iodine deficient and needs to begin supplementation. After determining an iodine deficiency, supplementation should begin gradually, because iodine mobilizes toxic metals and goitrogenic substances from their storage sites potentially increasing peripheral levels high enough to cause symptoms. Testing should be repeated every three to four months to monitor proper iodine doses."
Sources for Iodine Loading Test